DARS-AS1 accelerates the proliferation of cervical cancer cells via miR-628-5p/JAG1 axis to activate Notch pathway

Abstract Background Growing evidence has indicated the vital parts of long non-coding RNAs (lncRNAs) in modulating the progression of assorted human cancers, including cervical cancer (CC).Nevertheless, the role and mechanism of aspartyl-tRNA synthetase Bush antisense RNA 1 (DARS-AS1) have been not comprehensively illustrated in CC yet.Methods Real

read more



A novel framework for measuring software quality-in-use based on semantic similarity and sentiment analysis of software reviews

Software quality in use (QinU) relates to human-software interactions when a software product is used in a particular context.Currently, QinU measurement models are bound to ineffective measurement formulation and many models are subjectively incoherent.This paper proposes a novel QinU framework (QinUF) to measure QinU competently consuming softwar

read more

Remyelination protects neurons from DLK-mediated neurodegeneration

Abstract Chronic demyelination and oligodendrocyte loss deprive neurons of crucial support.It is the degeneration of neurons and their connections that drives progressive disability in demyelinating disease.However, whether chronic Cookware Sets demyelination triggers neurodegeneration and how it may do so remain unclear.We characterize two genetic

read more